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Peer-Reviewed Open Access Publication · ISSN: 2321-8681 · CC-BY 4.0 International

Open Access ISSN: 2321-8681 Volume: 13, Issue: 2 (July-December) 2026

Synthesis and Characterisation of Aldehyde-Amine Schiff Bases and Their Anti-Bacterial and Antifungal Properties

Authors: Ajay Ramdas Sonawane & Sagar dakhane India

Abstract

Schiff bases are organic compounds that contain an imine or azomethine linkage. These are typically written as –C=N– This review covers the basics of the reaction, factors affecting synthesis and how you can analyse your product. FTIR, NMR, UV-Vis, Mass Spectroscopy, Elemental Analysis and Melting Point can be used to give supporting evidence to show what your product is. There have been reports of some organic schiff bases being tested for anti bacterial and anti-fungal properties, however this varies depending on the structure of the molecule, the organism being tested, concentration and testing conditions. The lab results will not automatically mean the substance has anti-bacterial properties in reality. This review only focuses on schiff bases made from aldehydes and primary amines.

Keywords: Aldehyde, Primary amine, Schiff base, Imine, Condensation, FTIR, NMR, Anti-bacterial, Antifungal. Despite improvements in intensive care.

Journal Research and Reviews in Biotechnology and Biosciences
Peer Review Double-Blind Peer Reviewed
Publication Year 2026
Volume Volume: 13, Issue: 2 (July-December)
Page Range 76-85
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Ajay Ramdas Sonawane & Sagar dakhane (2026). Synthesis and Characterisation of Aldehyde-Amine Schiff Bases and Their Anti-Bacterial and Antifungal Properties. Research and Reviews in Biotechnology and Biosciences, Volume: 13, Issue: 2 (July-December) , 76-85. https://doi.org/10.5281/zenodo.23878909
Ajay Ramdas Sonawane & Sagar dakhane, 2026. Synthesis and Characterisation of Aldehyde-Amine Schiff Bases and Their Anti-Bacterial and Antifungal Properties. Research and Reviews in Biotechnology and Biosciences, Volume: 13, Issue: 2 (July-December) , pp. 76-85.
Ajay Ramdas Sonawane & Sagar dakhane. "Synthesis and Characterisation of Aldehyde-Amine Schiff Bases and Their Anti-Bacterial and Antifungal Properties." Research and Reviews in Biotechnology and Biosciences Volume: 13, Issue: 2 (July-December) (2026): 76-85.
@article{rrbb_334_AjayRamda, title = {{Synthesis and Characterisation of Aldehyde-Amine Schiff Bases and Their Anti-Bacterial and Antifungal Properties}}, author = {Ajay Ramdas Sonawane & Sagar dakhane}, journal = {Research and Reviews in Biotechnology and Biosciences}, issn = {2321-8681}, year = {2026}, volume = {Volume: 13, Issue: 2 (July-December) }, pages = {76-85}, doi = {https://doi.org/10.5281/zenodo.23878909} }
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source.