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Research & Reviews in Biotechnology and Biosciences

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TRANSITION METAL COMPLEX CATALYSED MANNICH REACTION OF PHENOL

Author Information
Name: Kulkarni Neha Shekhar & Shobha Waghmode
Email: sobhawaghmode@gmail.com
Country: India
Publication Details
Year: 2026
Volume: Volume: 13, Issue: 1, (January-June)
Page Number: 30-35
DOI: https://doi.org/10.5281/zenodo.18617128
Abstract
ABSTRACT
The mannich reaction is the most of the important carbon – carbon bond forming reactions in organic reactions . They involve the condensation of the aldehyde or ketones an amine. they forms as a beta amino carbonyl compound. Which is the important intermediate in pharmaceutical , or natural products, polymer chemistry. When combine with transition metal such as NI(II) , Cu(II), Co(II) these mannich bases ligand shows the stable
coordination complex with enhanced structural, catalytic and biological properties. This all-review focus on the synthesis , structural, catalytic behaviour of the transition metal complexesthey derived of the phenolic mannich bases. So, they contain the high purity solids with the good thermal stability.

Keywords:- In mannich reaction carbon carbon bond
formation product form beta amino ketone . Catalyst used :- Ni 2+ , Cu 2+, Co2+, Zn 2+. It enhanced catalytic properties.
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