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Peer-Reviewed Open Access Publication · ISSN: 2321-8681 · CC-BY 4.0 International

Open Access ISSN: 2321-8681 Volume: 12, Issue: 2, (July-December) 2025

Antiviral Properties of 1,3,4-Oxadiazole Derivatives Against Sars-2

Authors: Shama Parveen, Rishabh Bhardwaj, Madhu Sudan & Vikas Gupta India
Correspondence: drvikasgupta2510@gmail.com

Abstract

We describe the manufacture and biological evaluation of new,
potentially effective antibiotics against viruses that are 1,3,4-
oxadiazole substituted derivatives. Using a combination of mass
spectrometry, 1H NMR, IR, UV, and 13C NMR techniques, the
structures of the recently manufactured derivatives were established.
Since there aren't many clinically authorized treatments for the
COVID-19 pandemic yet, new ones must be developed by mid-2022.
This study examined three 1,3,4-oxadiazole derivatives' ability to
stop the SARS-2 virus from multiplying in the cultivation of cells.
One of the compounds described did not effectively stop the SARS-2
virus from reproducing.
Keywords: antiviral action, 1,3,4-oxadiazole, &1,3,4-oxadiazole
derivatives.

Journal Research and Reviews in Biotechnology and Biosciences
Peer Review Double-Blind Peer Reviewed
Publication Year 2025
Volume Volume: 12, Issue: 2, (July-December)
Page Range 25-32
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Shama Parveen, Rishabh Bhardwaj, Madhu Sudan & Vikas Gupta (2025). Antiviral Properties of 1,3,4-Oxadiazole Derivatives Against Sars-2. Research and Reviews in Biotechnology and Biosciences, Volume: 12, Issue: 2, (July-December) , 25-32. https://doi.org/10.5281/zenodo.16742908
Shama Parveen, Rishabh Bhardwaj, Madhu Sudan & Vikas Gupta, 2025. Antiviral Properties of 1,3,4-Oxadiazole Derivatives Against Sars-2. Research and Reviews in Biotechnology and Biosciences, Volume: 12, Issue: 2, (July-December) , pp. 25-32.
Shama Parveen, Rishabh Bhardwaj, Madhu Sudan & Vikas Gupta. "Antiviral Properties of 1,3,4-Oxadiazole Derivatives Against Sars-2." Research and Reviews in Biotechnology and Biosciences Volume: 12, Issue: 2, (July-December) (2025): 25-32.
@article{rrbb_263_ShamaParv, title = {{Antiviral Properties of 1,3,4-Oxadiazole Derivatives Against Sars-2}}, author = {Shama Parveen, Rishabh Bhardwaj, Madhu Sudan & Vikas Gupta}, journal = {Research and Reviews in Biotechnology and Biosciences}, issn = {2321-8681}, year = {2025}, volume = {Volume: 12, Issue: 2, (July-December) }, pages = {25-32}, doi = {https://doi.org/10.5281/zenodo.16742908} }
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