Cervical cancer is one of the most common and dangerous diseases in India and even globally which accounts for around 5% deaths per annum. Screening of cervical cancer is the only step which is proven to be most significant in prevention from high mortality rates. There are various types of techniques developed till date like liquid based cytology, HPV DNA testing and Pap tests which are helpful in screening of cervical cancer, but such techniques are associated with some kind of limitations related to sensitivity and specificity. It leads to the need of some novel technique which can provide results with high sensitivity and specificity. In the research for the same, there are many biomarkers which are developed till date. In this literature review, we will study characteristic features of p16 which acts as a cell cycle regulatory protein that has the ability to induce cell cycle arrest and one other Ki-67 which acts as cell proliferation marker.
Journal
Research and Reviews in Biotechnology and Biosciences
Peer Review
Double-Blind Peer Reviewed
Publication Year
2021
Volume
Volume-8, Issue-2 (July-December)
Cite this Article
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Shivam Bhardwaj, Dewashish Kaushik, Alokit Tanwar (2021). ROLE OF p16 AND Ki67 BIOMARKERS IN CERVICAL CANCER: A REVIEW. Research and Reviews in Biotechnology and Biosciences, Volume-8, Issue-2 (July-December).
Shivam Bhardwaj, Dewashish Kaushik, Alokit Tanwar, 2021. ROLE OF p16 AND Ki67 BIOMARKERS IN CERVICAL CANCER: A REVIEW. Research and Reviews in Biotechnology and Biosciences, Volume-8, Issue-2 (July-December).
Shivam Bhardwaj, Dewashish Kaushik, Alokit Tanwar. "ROLE OF p16 AND Ki67 BIOMARKERS IN CERVICAL CANCER: A REVIEW." Research and Reviews in Biotechnology and Biosciences Volume-8, Issue-2 (July-December) (2021).
@article{rrbb_182_ShivamBha,
title = {{ROLE OF p16 AND Ki67 BIOMARKERS IN CERVICAL CANCER: A REVIEW}},
author = {Shivam Bhardwaj, Dewashish Kaushik, Alokit Tanwar},
journal = {Research and Reviews in Biotechnology and Biosciences},
issn = {2321-8681},
year = {2021},
volume = {Volume-8, Issue-2 (July-December)}
}
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