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Research & Reviews in Biotechnology and Biosciences

A Biannual Peer Reviewed, Refereed Research Journal (Estd. Year: 2014) I Open Access Journal

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Archives Volume: 13, Issue: 1, (January-June)

TABLE OF CONTENTS

Paper Title:
STRUCTURAL AND MORPHOLOGICAL ANALYSIS OF GALLIUM OXIDE
Author Name:
Aysha Praveen Ansari & Rekha Rikhari
Author Email:
fos.rekha@mhu.edu.in
Country:
India
DOI:
https://doi.org/10.5281/zenodo.18240136
Page No.:
1-6
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STRUCTURAL AND MORPHOLOGICAL ANALYSIS OF GALLIUM OXIDE
Author: Aysha Praveen Ansari & Rekha Rikhari

ABSTRACT
Gallium oxide (Ga2O3) is a renowned semiconductor for its high band gap. Its strong surface sensitivity, chemical stability and thermal strength make it a promising candidate for sensors, power electronics, and UV detectors. To support these applications, the structural and morphological properties of Ga2O3 were investigated using scanning electron microscopy (SEM) and X ray diffraction (XRD). SEM analysis revealed a highly agglomerated morphology consisting of uneven, submicron-sized primary particles with coarse surface textures, indicating a large surface area and enhanced surface reactivity. XRD patterns confirmed the formation of the monoclinic β-
Ga2O3 phase, with sharp and intense diffraction peaks demonstrating high crystallinity and phase purity. Collectively, these results confirm the successful synthesis of highly crystalline Ga2O3 and highlight its potential for high temperature electronics, sensing platforms, optoelectronic
devices, and catalytic applications.

Keywords: Gallium Oxide; Semiconductor; Structural analysis

Paper Title:
BIOMEDICAL SIGNIFICANCE OF COORDINATION COMPOUNDS IN MODERN THERAPEUTICS
Author Name:
Deep Narayan Maurya, Vandana & Manoj Kumar Parjapati
Author Email:
mauryadeep343@gmail.com
Country:
India
DOI:
https://doi.org/10.5281/zenodo.18466974
Page No.:
7-15
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BIOMEDICAL SIGNIFICANCE OF COORDINATION COMPOUNDS IN MODERN THERAPEUTICS
Author: Deep Narayan Maurya, Vandana & Manoj Kumar Parjapati

ABSTRACT
Coordination compounds play a pivotal role in modern therapeutics due to their unique structural diversity, tunable reactivity, and ability to interact selectively with biological targets. In recent decades, advances in coordination chemistry have significantly expanded their biomedical applications, particularly in diagnosis, drug delivery, and treatment of complex diseases. Metal-based coordination compounds such as platinum, gold, copper, iron, and ruthenium complexes have demonstrated remarkable efficacy as anticancer, antimicrobial, anti-inflammatory, and antiviral agents. Their mechanisms of action often involve DNA binding, enzyme inhibition, redox activity, and modulation of cellular signaling pathways. Additionally, coordination compounds have been extensively explored in medical imaging, where metal complexes serve as contrast agents in techniques such as magnetic resonance imaging (MRI) and radiotherapy. The incorporation of
biocompatible ligands has further improved their selectivity, stability, and reduced toxicity, making them more suitable for clinical use. This review paper highlights the biomedical significance of coordination compounds in modern therapeutics, emphasizing their therapeutic potential,
mechanisms of action, and recent developments in metal-based drug design. The growing interdisciplinary approach, combining chemistry, biology, and medicine, suggests that coordination compounds will continue to make significant contributions to the development of next-generation therapeutic agents.

Keywords: Coordination compounds, Biomedical significance, Metal-based therapeutics, Anticancer drugs, Antimicrobial activity, Drug delivery systems, Medical imaging, Modern medicine.

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